Arthritis Treatment: How to Use Biomarkers to Treat Rheumatoid Arthritis

REJEKINE. Arthritis Treatment: How to Use Biomarkers to Treat Rheumatoid Arthritis

How to predict a patient's treatment is a blood test for rheumatoid arthritis that is the greatest?

Rheumatoid arthritis (RA) is a common form of inflammatory arthritis. This is the only damage to the joints of a systemic autoimmune condition, but there are good internal organ damage, even if the best treatment.

It was found in RA biomarker research in the science area, a lot of money. Biomarkers as predictive markers of tissue. It is the diagnoses, disease activity, and the treatment is used to predict the potential responses.

Biomarkers in various types. The first category is the antibody. These proteins, which are directed against the body produces an abnormal protein.

There are two examples. Rheumatoid factor in the first. 80 percent of the people, the RA antibodies that are present in blood. Rheumatoid factor is the high number of related, but after the initial diagnosis of the disease was low statistics. In addition, rheumatoid factor, syphilis, sarcoidosis, leprosy, and bacterial endocarditis (heart infection) can be elevated in other disease conditions.

Anti-cyclic citrullinated peptide antibody or other anti-CCP is a biomarker. Rheumatoid factors and disease severity and worse prognosis in the future, more and more specific to RA. Anti-CCP patients should be treated aggressively.

There is a biomarker of inflammation also contributes to patient treatment. Erythrocyte sedimentation rate of the old time honored test (ESR) or sed rate. ESR correlated with disease activity but not specific. Improve many of these diseases.

C-reactive protein or CRP is not a high disease activity and response to treatment more rapidly than the ESR correlation.

There are two other less known inflammatory biomarkers. Is an interferon. The anti-tumor necrosis factor a higher level than the patient will respond to a biological treatment.

Other inflammatory markers interleukin 1 receptor antagonist. Again, this marker is more likely a high level of anti-TNF therapy spandaneyagide.

To predict the severity of disease and response to treatment than do the more you can Biomarker levels of some drugs. He was the possibility of defects and disease, x-ray progression in many cases, there are mutual.

Some blood biomarkers to predict response to drugs, he felt different, but these theories have yet to be proven.