Rejekine. Uric acid is the result of metabolism in the body, whose levels are not excessive. Uric acid crystals have a shape that is the end result of purine metabolism, which is one basic organic compounds that make up nucleic acids (acid from the cell nucleus) and included in the group of amino acids, the building-blocks of proteins.
Everyone has uric acid in the body, because in any normal metabolism of uric acid is produced. Normally, uric acid will be expelled from the body through the stool (feces) and urine, but because the kidneys are unable to remove uric acid that is causing increased levels in the body. Another thing that can increase uric acid levels is that we consume too many foods that contain lots of purines. Further excess uric acid will accumulate in the joints, causing pain or swelling.
Foods from animal source products usually contain very high purine. High purine-containing food products is not good for certain people, who have talent impaired uric acid. If you eat these foods without any calculation, the amount of purines in the body can pass through the normal threshold.
Some foods and drinks that are known to increase uric acid levels are alcohol, fish hearing, eggs, and offal. Hearings or similar fish (sardines), and the innards are a source of potential compounds. Offal belonging not only the intestine but all other parts contained in the stomachs of animals, such as liver, heart, tripe, and spleen. Consumption of offal aggravate the enzyme hypoxanthine to process purines. Consequently, many of the rest of uric acid in the blood, which shaped grains and accumulate around the joint so it creates a feeling very sick.
Normal Levels of Uric Acid
Uric acid levels can be measured in two ways, enzymatic and Engineering Ordinary. Normal uric acid levels by an enzymatic test a maximum of 7 mg / dl. While the technique Ordinary, normal values up to 8 mg / dl. Uric acid levels above normal is called hyperuricemia.
Normal uric acid levels in men and women are different. Normal uric acid levels in men ranged from 3.5 to 7 mg / dl and in women from 2.6 to 6 mg / dl.
Disease Uric Acid (Gout)
Someone said to suffer from uric acid (gout) if the conditions meet several requirements and usually once a classical course of their illness, such as having the typical symptoms of gout, uric acid found in high levels in their blood, and the results of microscopic examination of joint fluid or tofus (lumps of uric acid ) found uric acid crystals in the form of needles.
Diseases of uric acid (gout) is classified into primary gout and secondary gout.
In primary gout, 99 percent of the cause is unknown (idiopathic). Allegedly associated with a combination of genetic factors and hormonal factors that cause metabolic disturbances that may result in increased production of uric acid or it could be caused by the reduction in expenditure of uric acid from the body.
Secondary gout is caused partly because of the increased production of uric acid due to nutrients, ie foods with high purine levels.
Increased production of uric acid could also be due to diseases of the blood (bone marrow disease, polycythemia), drugs (alcohol, cancer medications, vitamin B12). Other causes are obesity (overweight), skin diseases (psoriasis), high triglyceride levels. In people with diabetes are not well controlled levels typically found ketone bodies (waste product of fat metabolism) are rising. Ketone bodies that rise will also cause elevated uric acid.
Arthritis due to increased blood uric acid levels with arthritis called gout or arthritis arthritis. Acute gouty arthritis is caused by an inflammatory reaction of tissues to the formation of urate crystals. In most cases of gout history of the disease and the clinical picture is specific, so sometimes the diagnosis can be directly enforced.
Selasa, 03 Januari 2012
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