Hepatitis C Drugs

rejekine. Hepatitis C is currently the standard drug is a combination of Interferon with Ribavirin. Hepatitis C drug combination is going to result in sustained virologic response (persistent viral response) is high. Response is often abbreviated as SVR.

Hepatitis C drugs pegylated interferon alfa created by combining a large water-soluble molecules called "polyethylene glycol" (PEG) with alpha interferon molecule. Merger with PEG interferon alpha increases the size so that it can survive in the body longer. It also can protect the interferon molecule divided by body enzymes.

Another advantage is the time in the body of Hepatitis C drug is much longer (half-life) so did not need to Hepatitis C drug often consumed. Interferon alfa usual standards injected three times a week but pegylated interferon alfa just once a week.

In addition, research showed the drug pegylated interferon alfa Hepatitis C is more effective in producing a response against the virus in patients with chronic hepatitis C than interferon alfa that did not experience pegylasi.

Currently there are two kinds of pegylated interferon alfa are available: peginterferon alfa-2a and peginterferon alfa-2b. although both compounds are effective in the treatment of chronic hepatitis C, there is a difference in the size, type pegylasi, the half-life, route penbersihan of the body and a second dose of pegylated interferon.

Because pegylasi method and type of PEG molecule used in the process can affect the action of drugs and cleaning processes in the body.

The big difference between the two pegylated interferons is dose. The dose of pegylated interferon alfa-2a is the same for all patients, not considering the weight and size of the patient.

While the dose of pegylated interferon alfa-2b adjusted to individual patient's body weight.

Hepatitis C drug is administered according to body weight of patients at a dose of 1.5 mg / kg body weight. Hepatitis C drug is now also available in the form of a pen (Peg Intron Redipen). Form the pen of hepatitis C drugs will provide convenience to patients in the injection. This will increase the ease of patient compliance in the treatment of Hepatitis C. Compliance in the treatment of Hepatitis C is an important factor in improving the therapeutic efficacy of hepatitis C.