Kamis, 28 Maret 2013

Coronary heart disease and grapefruit juice interactions

Grapefruit juice has a magic ability to help your Heart medication to be increased in your blood and enhancing pharmaceuticals metabolism for heart medications and prevent coronary heart disease with help of calcium channel blockers that lowering blood hypertension, although grapefruit juice does not affect medication such as diltiazem but still Grapefruit juice affect some medications such as:
amlodipine, felodipine, isradipine, lacidipine, lercanidipine, nicardipine, nifedipine, nimodipine, verapamil, and Ciclosporin immunosuppressants like sirolimus, tacrolimus, in addition to Entocort (treats Crohn’s disease), Cytotoxic medicines and Aliskiren.
Also Grapefruit juice may enhance drug toxicity for antiarrhythmic agents such as for congestive heart failure drugs

Such drugs interactions may increase the risk of rhabdomyolysis and heart attacks, please don’t drink Grapefruit juice if your medication including one of that medicines.
So in case of that medicines you only one glass of Grapefruit juice will be good

Grapefruit juice nutrition value to compare affect of Grapefruit on coronary artery drugs
Grapefruit
Per 1/2 medium - Calories: 41kcal | Fat: 0.13g | Carbohydrates: 10.34g | Protein: 0.81g
Other sizes: 1/2 small - 32kcal, 1/2 large - 53kcal, 1 cup - 74kcal
Grapefruit (Pink and Red) Per 1/2 fruit - Calories: 52kcal | Fat: 0.17g | Carbohydrates: 13.11g | Protein: 0.95g
Other sizes: 1 cup sections, with juice - 97kcal, 1 NLEA serving - 65kcal, 1 oz - 12kcal
Florida Pink and Red Grapefruit Per 1/2 fruit - Calories: 37kcal | Fat: 0.12g | Carbohydrates: 9.22g | Protein: 0.68g
Other sizes: 1 cup sections, with juice - 69kcal, 1 oz - 9kcal, 100 g - 30kcal
California White Grapefruit Per 1/2 fruit - Calories: 44kcal | Fat: 0.12g | Carbohydrates: 10.73g | Protein: 1.04g
Other sizes: 1 cup sections, with juice - 85kcal, 1 oz - 10kcal, 100 g - 37kcal

What is the best diet including grapefruit and not affect heart arteries?
A Diet low of saturated fats such as foods high in cholesterol and foods rich in fibers such as fruits and vegetables or nuts and seeds will help prevent coronary heart disease.
Grapefruit is a good source of vitamin C that is the important factor in heart disease prevention 

Eating red grapefruit not Orange grapefruit helps reduce cholesterol and triglycerides in people who already have heart disease while statins is usually used to treat high cholesterol and triglycerides.

How grapefruit affect heart medications? Interaction Mechanism including regulation of intestinal receptors by grapefruit juice consumption, Grapefruit binds the drugs to bring them into the blood circulation; there is a known problem with quinidex and grapefruit juice while the interactions with mexitil are unknown.
Hope it will help you.

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